[BioC] method and package for imputing spectral counts from masspectrometry

[Moshe Olshansky]

Hi Yolande,

Do you mean the raw counts coming out of the instrument before any preprocessing?

Regards,
Moshe.

--- On Tue, 26/10/10, Yolande Tra <yolande.tra at gmail.com> wrote:

> From: Yolande Tra <yolande.tra at gmail.com>
> Subject: [BioC] method and package for imputing spectral counts from masspectrometry
> To: bioconductor at stat.math.ethz.ch
> Received: Tuesday, 26 October, 2010, 11:11 AM
> Hello list members,
> 
> I would like to start a new thread here. Does anyone have
> experience
> in imputing spectral counts from mass spectrometry? I have
> used
> na.roughfix followed by RFImpute in Random Forest package
> to impute
> the missing spectral counts. It seems that the imputation
> brought
> skewness in the data. I believe, there must be a solution,
> instead of
> filling in a zero.
> 
> Thank you for sharing your experience.
> Yolande
> 
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