[BioC] method and package for imputing spectral counts from masspectrometry

[Yolande Tra]

Yes.

Yolande

On Tue, Oct 26, 2010 at 1:56 AM, Moshe Olshansky <m_olshansky at yahoo.com> wrote:
> Hi Yolande,
>
> Do you mean the raw counts coming out of the instrument before any preprocessing?
>
> Regards,
> Moshe.
>
> --- On Tue, 26/10/10, Yolande Tra <yolande.tra at gmail.com> wrote:
>
>> From: Yolande Tra <yolande.tra at gmail.com>
>> Subject: [BioC] method and package for imputing spectral counts from masspectrometry
>> To: bioconductor at stat.math.ethz.ch
>> Received: Tuesday, 26 October, 2010, 11:11 AM
>> Hello list members,
>>
>> I would like to start a new thread here. Does anyone have
>> experience
>> in imputing spectral counts from mass spectrometry? I have
>> used
>> na.roughfix followed by RFImpute in Random Forest package
>> to impute
>> the missing spectral counts. It seems that the imputation
>> brought
>> skewness in the data. I believe, there must be a solution,
>> instead of
>> filling in a zero.
>>
>> Thank you for sharing your experience.
>> Yolande
>>
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>