[BioC] method and package for imputing spectral counts from masspectrometry

[Yolande Tra]

Hello list members,

I would like to start a new thread here. Does anyone have experience
in imputing spectral counts from mass spectrometry? I have used
na.roughfix followed by RFImpute in Random Forest package to impute
the missing spectral counts. It seems that the imputation brought
skewness in the data. I believe, there must be a solution, instead of
filling in a zero.

Thank you for sharing your experience.
Yolande