[BioC] mean versus linear model?
Simon Melov
smelov at buckinstitute.org
Mon Jan 12 03:21:00 MET 2004
Not being a statistician, I was wondering if there were a
straightforward answer as to why using a linear model was "better" than
a straight mean in limma when estimating the average M value across
multiple chips. I believe that the regression analysis is supposed to
be less influenced by outliers, is this the chief reason the linear
model is implemented?
thanks
Simon.
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