[R-meta] overall efect size from subgroup analysis
Michael Dewey
||@t@ @end|ng |rom dewey@myzen@co@uk
Wed Apr 28 14:14:56 CEST 2021
Dear Diego
I think the section entitled Separate meta-analyses covers what you want
to do.
Michael
On 28/04/2021 08:10, Diego Grados Bedoya wrote:
> Dear Michael,
>
> Sorry, I did not notice that the email was mangled.
>
> Thank for the link but I do not have access to the original data of the
> subgroups. I just have the effect sizes, CIs and number of comparisons
> (observations).
>
> subgroup CI_lower_limit effect_size CI_upper_limit number_comparisons
> group_1 -73 -48 -12 5
> group_2 -38 -30 -21 43
> group_3 -24 -15 -6 73
>
> Greetings,
>
> Diego
>
> On Tue, 27 Apr 2021 at 16:08, Michael Dewey <lists using dewey.myzen.co.uk
> <mailto:lists using dewey.myzen.co.uk>> wrote:
>
> Dear Diego
>
> I think you may find
> https://metafor-project.org/doku.php/tips:comp_two_independent_estimates
> <https://metafor-project.org/doku.php/tips:comp_two_independent_estimates>
> helpful.
>
> Your data is close to unreadable as you posted in HTML and that becomes
> mangled. If you need to re-post you have to find a way to send plain
> text. I do not use Gmail but I am sure it is possible.
>
> Michael
>
> On 27/04/2021 08:56, Diego Grados Bedoya wrote:
> > Dear all,
> >
> > Several meta-analyses in my field do not report the overall
> effect size of
> > the intervention. For instance, they report the subgroup
> analysis (values
> > as a percentage change for log response ratio):
> >
> > subgroup
> >
> > CI_lower_limit
> >
> > effect_size
> >
> > CI_upper_limit
> >
> > number_comparisons
> >
> > group_1
> >
> > -73
> >
> > -48
> >
> > -12
> >
> > 5
> >
> > group_2
> >
> > -38
> >
> > -30
> >
> > -21
> >
> > 43
> >
> > group_3
> >
> > -24
> >
> > -15
> >
> > -6
> >
> > 73
> >
> > Assuming a random effect model (and considering that the CI of the
> > subgroups could have been estimated by bootstrapping), I wonder
> if it is
> > possible to estimate the overall effect size and the CIs just
> with this
> > information?
> >
> > Thank you in advance,
> >
> > Kind regards,
> >
> > Diego
> >
> > [[alternative HTML version deleted]]
> >
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>
> --
> Michael
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> <http://www.dewey.myzen.co.uk/home.html>
>
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