[R-meta] overall efect size from subgroup analysis

Michael Dewey ||@t@ @end|ng |rom dewey@myzen@co@uk
Wed Apr 28 14:14:56 CEST 2021


Dear Diego

I think the section entitled Separate meta-analyses covers what you want 
to do.

Michael

On 28/04/2021 08:10, Diego Grados Bedoya wrote:
> Dear Michael,
> 
> Sorry, I did not notice that the email was mangled.
> 
> Thank for the link but I do not have access to the original data of the 
> subgroups. I just have the effect sizes, CIs and number of comparisons 
> (observations).
> 
> subgroup CI_lower_limit effect_size CI_upper_limit number_comparisons
> group_1 -73 -48 -12 5
> group_2 -38 -30 -21 43
> group_3 -24 -15 -6 73
> 
> Greetings,
> 
> Diego
> 
> On Tue, 27 Apr 2021 at 16:08, Michael Dewey <lists using dewey.myzen.co.uk 
> <mailto:lists using dewey.myzen.co.uk>> wrote:
> 
>     Dear Diego
> 
>     I think you may find
>     https://metafor-project.org/doku.php/tips:comp_two_independent_estimates
>     <https://metafor-project.org/doku.php/tips:comp_two_independent_estimates>
>     helpful.
> 
>     Your data is close to unreadable as you posted in HTML and that becomes
>     mangled. If you need to re-post you have to find a way to send plain
>     text. I do not use Gmail but I am sure it is possible.
> 
>     Michael
> 
>     On 27/04/2021 08:56, Diego Grados Bedoya wrote:
>      > Dear all,
>      >
>      > Several meta-analyses in my field do not report the overall
>     effect size of
>      > the intervention. For instance, they report  the subgroup
>     analysis (values
>      > as a percentage change for log response ratio):
>      >
>      > subgroup
>      >
>      > CI_lower_limit
>      >
>      > effect_size
>      >
>      > CI_upper_limit
>      >
>      > number_comparisons
>      >
>      > group_1
>      >
>      > -73
>      >
>      > -48
>      >
>      > -12
>      >
>      > 5
>      >
>      > group_2
>      >
>      > -38
>      >
>      > -30
>      >
>      > -21
>      >
>      > 43
>      >
>      > group_3
>      >
>      > -24
>      >
>      > -15
>      >
>      > -6
>      >
>      > 73
>      >
>      > Assuming a random effect model (and considering that the CI of the
>      > subgroups could have been estimated by bootstrapping), I wonder
>     if it is
>      > possible to estimate the overall effect size and the CIs just
>     with this
>      > information?
>      >
>      > Thank you in advance,
>      >
>      > Kind regards,
>      >
>      > Diego
>      >
>      >       [[alternative HTML version deleted]]
>      >
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> 
>     -- 
>     Michael
>     http://www.dewey.myzen.co.uk/home.html
>     <http://www.dewey.myzen.co.uk/home.html>
> 
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Michael
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