[R-sig-genetics] Linkage disequilibrium estimation
Zhian Kamvar
zkamvar at gmail.com
Mon Nov 21 17:22:28 CET 2016
> On Nov 21, 2016, at 06:27 , Felipe Hernández <fhernandeu at uc.cl> wrote:
>
> On the other hand, I wonder is there is another package to test LD between
> several multi-allelic loci at the same time (not only two loci)? Thanks for
> your feedback!
Hi Felipe,
There IS another method that can test LD between several loci. The index of association is a measure of multilocus linkage disequilibrium [0] and is implemented in the poppr R package with the function ia(). You can use it on a genind object, which can be converted from loci with the function loci2genind().
Best,
Zhian
[0]: http://onlinelibrary.wiley.com/doi/10.1046/j.1471-8278.2000.00014.x/abstract
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