[BioC] Repitools - featureScores - mappability Bsgenome object
Jaritz,Markus
Markus.Jaritz at imp.ac.at
Thu Feb 27 12:20:04 CET 2014
Dear colleagues,
dear Mark,
Many thanks for providing the "Repitools "package, it is of great help.
There, the function "featureScores" allows for considering mappability for reads
via a BSgenome object.
Is there any such "mappability-based" BSgenome available,
especially for Mus musculus? I could not find one
(not even the one mentioned in the Repitools vignette,
"BSgenome.Hsapiens36bp.UCSC.hg18mappability_1.0").
In case there is none, I assume I need to forge
my own mappability masked version of the Mus musculus
genome (or several, for each read length), and provide this
as a parameter to the featureScores function? Or is this
an overkill and masking just the regions considered
in the analysis (e.g., peak regions) is sufficient?
Thank you for any hint!
Kind regards
Markus
Dr. Markus Jaritz
IMP - Research Institute of Molecular Pathology
sessionInof()
R version 2.15.2 (2012-10-26)
Platform: x86_64-pc-linux-gnu (64-bit)
locale:
[1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
[3] LC_TIME=de_AT.UTF-8 LC_COLLATE=en_US.UTF-8
[5] LC_MONETARY=de_AT.UTF-8 LC_MESSAGES=en_US.UTF-8
[7] LC_PAPER=C LC_NAME=C
[9] LC_ADDRESS=C LC_TELEPHONE=C
[11] LC_MEASUREMENT=de_AT.UTF-8 LC_IDENTIFICATION=C
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] BiocInstaller_1.8.3 Biobase_2.18.0
[3] Repitools_1.4.2 BSgenome.Mmusculus.UCSC.mm9_1.3.19
[5] BSgenome_1.26.1 Biostrings_2.26.3
[7] GenomicRanges_1.10.7 IRanges_1.16.6
[9] BiocGenerics_0.4.0
loaded via a namespace (and not attached):
[1] edgeR_3.0.8 limma_3.14.4 parallel_2.15.2 stats4_2.15.2
[5] tcltk_2.15.2 tools_2.15.2
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