[BioC] Why nbinomGLMTest in DESeq reports zero p values
Yanzhu [guest]
guest at bioconductor.org
Fri Feb 7 17:51:08 CET 2014
I used nbinomGLMTest to compare the reduced model and full model given as below, and I got some zero for p values. Is this possible for nbinomGLMTest? If so, what's the potential reason? Thanks
Full model:
full<-fitNbinomGLMs(cdsFull,count~Line+Rep+Sex)
Reduced model:
reduced<-fitNbinomGLMs(cdsFull,count~Line+Rep)
-- output of sessionInfo():
sessionInfo()
R version 3.0.1 (2013-05-16)
Platform: x86_64-w64-mingw32/x64 (64-bit)
locale:
[1] LC_COLLATE=English_United States.1252 LC_CTYPE=English_United States.1252 LC_MONETARY=English_United States.1252
[4] LC_NUMERIC=C LC_TIME=English_United States.1252
attached base packages:
[1] parallel stats graphics grDevices utils datasets methods base
other attached packages:
[1] DESeq_1.12.1 lattice_0.20-15 locfit_1.5-9.1 Biobase_2.20.1 BiocGenerics_0.6.0 edgeR_3.2.4 limma_3.16.8
loaded via a namespace (and not attached):
[1] annotate_1.38.0 AnnotationDbi_1.22.6 DBI_0.2-7 genefilter_1.42.0 geneplotter_1.38.0 grid_3.0.1
[7] IRanges_1.18.4 RColorBrewer_1.0-5 RSQLite_0.11.4 splines_3.0.1 stats4_3.0.1 survival_2.37-4
[13] XML_3.98-1.1 xtable_1.7-1
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