[BioC] Two-way ANOVA with multtest's MTP/EBMTP
Neil Gray
nag2103 at columbia.edu
Wed Jan 19 22:12:13 CET 2011
Hello - hopefully a quick question here. I've been using the MTP and
EBMTP functions for multiple testing correction of microarray
expression data. I've had no problems using the t-test option, but my
overall design is a two-factor ANOVA (2x2 groups using two different
treatments). My eSet therefore has two phenoData slots, and while it's
easy enough to specify one or the other, e.g.,
test='t.twosamp.equalvar' and Y='treatment1', but I don't understand how
to specify the 2x2 design for test='f.twoway'. It seems Y can't be a
matrix, and it can only be of length equal to the number of samples.
So, given that 12 samples with groups defined as
treatment1=c(0,0,0,0,0,0,1,1,1,1,1,1) and
treatment2=c(0,0,0,1,1,1,0,0,0,1,1,1), how do I pass this design to MTP?
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