[BioC] Mapping chromosome and nucleotide position to gene name
Steven McKinney
smckinney at bccrc.ca
Fri Apr 17 00:08:30 CEST 2009
Thanks Steve,
The thread ideas work beautifully.
Thanks also to Martin Morgan for his ideas.
Best
Steve McKinney
> -----Original Message-----
> From: Steve Lianoglou [mailto:mailinglist.honeypot at gmail.com]
> Sent: Thursday, April 16, 2009 1:03 PM
> To: Steven McKinney
> Cc: bioconductor at stat.math.ethz.ch
> Subject: Re: [BioC] Mapping chromosome and nucleotide position to gene
> name
>
> Hi,
>
> On Apr 16, 2009, at 3:51 PM, Steven McKinney wrote:
>
> > Hi all,
> >
> >> From the output of a custom HMM routine,
> > I have data showing chromosome number and nucleotide position,
> > but no associated gene name or database identifier. e.g.
> >> logRiList[[1]][1:10,]
> > chromosome position end logR state
> > 1 1 10004 10004 0.7627 3
> > 2 1 46844 46844 -0.1648 3
> > 3 1 59415 59415 0.1096 3
> > 4 1 97215 97215 0.5914 3
> > 5 1 224176 224176 0.6766 3
> > 6 1 227744 227744 0.7047 3
> > 7 1 311662 311662 0.4185 3
> > 8 1 314893 314893 0.9843 3
> > 9 1 318309 318309 0.2642 3
> > 10 1 320085 320085 0.7877 3
> >
> > How can I map this data to RefSeq Accession number or EntrezGene ID
> > etc. so
> > I can get the name of the gene associated with a given chromosome
> > and nucleotide
> > position?
>
> I'm not sure if this is optimal, but it's quite similar to what the
> poster was trying to do in this thread:
>
>
http://thread.gmane.org/gmane.science.biology.informatics.conductor/2144
5
>
> See Martin Morgan's response for an idea of how to take a crack at it
> using your organism's GTF/GFF and the IRanges package.
>
> HTH,
>
> -steve
>
> --
> Steve Lianoglou
> Graduate Student: Physiology, Biophysics and Systems Biology
> Weill Medical College of Cornell University
>
> http://cbio.mskcc.org/~lianos
>
>
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