[BioC] Normalizing two different platforms
Kasper Daniel Hansen
khansen at stat.Berkeley.EDU
Fri Feb 29 00:13:51 CET 2008
There are many posts dealing with this exact problem for these exact
chips (for this exact reason I guess). Search the archives.
Kasper
On Feb 26, 2008, at 12:07 PM, Yair Benita wrote:
> Dear R members,
> I have this problem with 2 different Affy platforms. We started the
> experiment with U133A chips but had to switch in the middle to
> U133A_plus2.
> All the U133A are backordered with no delivery in sight. The two
> chips have
> the exact same gene probes and differ only in a few control probes.
> Naturally I will get an error in gcrma or ReadAffy but I was
> wondering if
> there is an easy way around this that will allow me to still
> normalize all
> my arrays together. Can I just ignore the control probes somehow?
> Maybe I
> need to modify the CDF file but I am not sure how complicated this is.
>
> Thanks,
> Yair
>
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