[BioC] Cutoff for non-specific gene filtering?

[Sean Davis]

On Wed, Apr 30, 2008 at 9:47 AM, Suraj Menon <menons1 at cardiff.ac.uk> wrote:
> Hi all
>
>  Am curious to know why the recommended cutoff to remove non-variable genes is an IQR of 0.5.
>  What is the significance of this number?

There is not any recommendation that I know of.  You will need to
define your own cutoffs, generally.

>  Also, why use IQR as opposed to any other measure of variability, like SD?

You can choose any measure that you like.  IQR is less sensitive to
outliers than SD, generally.

Sean