[BioC] Cutoff for non-specific gene filtering?

[Suraj Menon]

Hi all

Am curious to know why the recommended cutoff to remove non-variable genes is an IQR of 0.5.
What is the significance of this number?
Also, why use IQR as opposed to any other measure of variability, like SD?

Cheers
-Suraj

Suraj Menon
PhD Student
Department of Pathology
Henry Wellcome Building
School of Medicine
Cardiff University
Heath Park
Cardiff CF14 4XN

Tel:    +44 29 2074 3979
Email: MenonS1 at Cardiff.ac.uk