[BioC] Manufacturer ids in lumiHumanV1
Sean Davis
sdavis2 at mail.nih.gov
Thu Jul 5 14:43:43 CEST 2007
Benjamin Otto wrote:
> Dear bioconductors,
>
> I just installed the lumiHumanV1 package via the biocLite() procedure
> yesterday. The identifiers of the single probes look very strange to me.
> Beside that they don't appear in the annotation file provided by Illumina
> the name composition itself made me, let me say somehow suspicious! Here
> comes a quick extract. Did someone observe that before?
>
>
>> xx <- as.list(lumiHumanV1ACCNUM)
>> xx[1:5]
>>
> $x00WAIBIVaMvS3EVQ0
> [1] NA
>
> $`9iFKOnl5SKK4SnkAS8`
> [1] "NM_032360"
>
> $Ke_INOf6KSdNz6Qeek
> [1] "NM_030945"
>
> $rKBxx.U0SoWkRRVxac
> [1] "NM_025258"
>
> $ilenrd0XnE.4v_3Zec
> [1] NA
>
>
>> sessionInfo()
>>
> R version 2.5.0 (2007-04-23)
> i386-pc-mingw32
>
> locale:
> LC_COLLATE=English_United States.1252;LC_CTYPE=English_United
> States.1252;LC_MONETARY=English_United
> States.1252;LC_NUMERIC=C;LC_TIME=English_United States.1252
>
> attached base packages:
> [1] "tools" "stats" "graphics" "grDevices" "utils" "datasets"
> [7] "methods" "base"
>
> other attached packages:
> lumiHumanV1 lumi annotate mgcv affy affyio
> "1.2.0" "1.2.0" "1.14.1" "1.3-23" "1.14.0" "1.4.0"
> Biobase
> "1.14.0"
>
These IDs are nuIDs. They are used by the lumi package and are a
base-64 encoded version of the actual sequence of the probe. You may
find that the "illumina...." data packages, rather than the "lumi...."
data packages have the standard keys. However, if you are using the
lumi package for dealing with Illumina data, the "lumi...." data
packages will work just fine. Perhaps Pan Du or Simon Lin will fill in
some more details about why they use nuID.
Sean
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