[BioC] usage of "all" category in annotation data
Michael Newton
newton at stat.wisc.edu
Thu Aug 9 23:06:05 CEST 2007
I'm seeking advice on the use of the "all" component in various
annotation data packages relative to GO.
Using R version 2.4.1 and (e.g.) hgu133plus version 1.14.0,
library(hgu133plus2) ## an Affy data package
x <- as.list( hgu133plus2GO2ALLPROBES ) ##probe sets for each GO term
xa <- unique( x[["all"]] ) ## holds probe sets associated to "all"
xbp <- unique( x[["GO:0008150"]] ) # biological process
xmf <- unique( x[["GO:0003674"]] ) # molecular function
xcc <- unique( x[["GO:0005575"]] ) # cellular component
## note that the following is true
all( xa == xbp )
But further checks show that the molecular function probe sets are not
a subset of "all".
I was under the impression that "all" is the union of MF, BP, and CC,
but in the few libraries I've checked, "all" equals BP. I haven't
found a discussion of the matter in the few vignettes that might be
relevant.
Is "all" really "BP", or is it supposed to be the union?
thanks,
-Michael N.
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