[BioC] Comparing limma results of two different groupings
Daniel Brewer
daniel.brewer at icr.ac.uk
Fri Aug 3 17:01:53 CEST 2007
I have been using limma to do differential analysis between two
different groupings, both splitting the samples into two groups. The
results for one set give approx. 100 significant genes (adj.
p-value<0.05) whereas the other gives approx. 1000 significant genes.
Is this suggestive that the second grouping is more "accurate" than the
other? What is the best way to test this in a statistical manner.
Many thanks
--
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Daniel Brewer, Ph.D.
Institute of Cancer Research
Email: daniel.brewer at icr.ac.uk
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The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP.
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