[BioC] normalization of colonCA data
Seth Falcon
sfalcon at fhcrc.org
Tue Nov 29 21:09:20 CET 2005
Hi Rebecca,
On 28 Nov 2005, pmt1rew at leeds.ac.uk wrote:
> I would like to used the colonCA and golub datasets in some work
> that I am preparing. Whilst the golub data has been pre-processed
> of sorts, I would like to normalize the colonCA data with vsn etc.
> How do I work this function on an exprSet? Or how do I get the data
> back into a form from which I can proceed as normal?
If you have an exprSet, you can get the expression matrix using the
exprs method. E.g.,
mat <- exprs(myExprSet)
If vsn doesn't operate on exprSet objects, that might be a nice
improvement. You might want to look at getIntensityMatrix in vsn, I
think that function knows about exprSet objects.
+ seth
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