[BioC] average linkage clustering in Eisen's Cluster vs. that in hclust

Wittner, Ben Wittner.Ben at mgh.harvard.edu
Tue Nov 29 19:27:13 CET 2005

Eisen's cluster software implements average linkage clustering by replacing
nodes with an average of the leaf nodes represented by the node and by then
computing distances from that average. hclust(), on the other hand, uses an
average of the distances between all pairs of points in two nodes.

Does anyone have any information/opinion as to why one method might be better
than the other?

Also, does anyone know of any code in R that implements Eisen's algorithm?



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