[BioC] Re: limma t-tests and SAM

[Dennis Hazelett]

Perhaps you'll find <a 
href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12112249">this 
paper</a> useful.
--Dennis

Hi

  I have one other question is there an article somewhere which 
explains in a manner a non statistician might understand the 
difference between an analysis by limma and paired t-tests and SAM. 
We have now done all three and are trying to decide which analysis to 
give most weight to  (our experiment compared wild type to mutant, 
increased dosage to wild type and as the mutant was ts a temperature 
variable) in choosing which genes to verify and follow up on.

thanks,

Simon