[BioC] factdesign package

Claire Wilson ClaireWilson at PICR.man.ac.uk
Tue May 4 16:33:43 CEST 2004

Dear all,

I have been working through the factdesign vignette and was wondering
why only 500 genes are used. The data given are derived from Affymetrix
HGU95av2 chips that have been normalised using RMA. I believe the U95av2
chips measure the abundance of ~12,000 transcripts. Is the filtering of
genes from 12,000 to 500 done purely for size reasons and if so how were
these 500 selected? If not what criteria were used to select the 500

Many thanks


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