[BioC] tissue contamination problem in microarray

[Wolfgang Huber]

Hao Liu wrote:
> 
> I would like to know if there are techniques to minimize the perturbation
> caused by tissue contamination, for example, normal lung tissue
> contamination on a breast metastasis. What is the best strategy to deal
> with this problem? 
> 
> I think this should be dealt with at the "low" level normalization
> process, please help.

I think it should be dealt with at the level of tissue extraction, i.e. 
use microdissection.

Best wishes
   Wolfgang

-- 
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Wolfgang Huber
Division of Molecular Genome Analysis
German Cancer Research Center
Heidelberg, Germany
Phone: +49 6221 424709
Fax:   +49 6221 42524709
Http:  www.dkfz.de/abt0840/whuber