[BioC] tissue contamination problem in microarray

Wolfgang Huber w.huber at dkfz-heidelberg.de
Mon May 3 23:17:44 CEST 2004

Hao Liu wrote:
> I would like to know if there are techniques to minimize the perturbation
> caused by tissue contamination, for example, normal lung tissue
> contamination on a breast metastasis. What is the best strategy to deal
> with this problem? 
> I think this should be dealt with at the "low" level normalization
> process, please help.

I think it should be dealt with at the level of tissue extraction, i.e. 
use microdissection.

Best wishes

Wolfgang Huber
Division of Molecular Genome Analysis
German Cancer Research Center
Heidelberg, Germany
Phone: +49 6221 424709
Fax:   +49 6221 42524709
Http:  www.dkfz.de/abt0840/whuber

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