[BioC] Re: Bioconductor Digest, Vol 11, Issue 12

Stephen P. Baker stephen.baker at umassmed.edu
Sat Jan 10 15:44:11 MET 2004

Bioconductor Digest, Vol 11, Issue 12In my previous post should have said "...any effect  that is significant by ANOVA with RMA or PM only estimates would also be evidence of presence EXCEPT for intercept terms as there will always be nonspecific binding. 
  ----- Original Message ----- 
  From: Stephen P. Baker 
  To: bioconductor at stat.math.ethz.ch 
  Sent: Saturday, January 10, 2004 8:47 AM
  Subject: Re: Bioconductor Digest, Vol 11, Issue 12

  I would think that ANY significant differential expression by ANOVA is evidence of presence.  Also if using MAS5 or LiWong PM-MM, any significant effect including intercept would be evidence of presence but I don't think the same can be said of RMA or PM only estimates.

  -.- -.. .---- .--. ..-.
  Stephen P. Baker, MScPH , PhD(ABD)                      (508) 856-2625
  Senior Biostatistician                                                     (775) 254-4885 fax
  Information Services Bioinformatics Unit
  Lecturer in Biostatistics , Graduate School of Biomedical Sciences
  University of Massachusetts Medical School
  55 Lake Avenue North                          stephen.baker at umassmed.edu
  Worcester, MA 01655  USA

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