[Bioc-sig-seq] Illumina vs. ABI Solid

Steve Lianoglou mailinglist.honeypot at gmail.com
Wed Dec 23 03:02:49 CET 2009


2009/12/22 Droit Arnaud <Arnaud.Droit at ircm.qc.ca>:
> Hi all,
> The institute where I currently work is in the process of buying a new HT sequencer. We are debating whether we should get an Illumina or a Solid sequencer. I was wondering if anyone of you could give me some advice in terms of analysis. As a bioinformatician using R, I am particularly interested in comparisons in terms of analysis, data manipulation/storage in R, etc. We have some experience analyzing Illumina data but no experience with Solid data.

For whatever its worth, we had someone from The Broad recently give a
talk about some work he's been doing with RNA-seq.

Near the beginning of the talk he had a slide with the number of
machines they had from each platform, it broke down to something
roughly like so (if I remember correctly):

Illumina: ~ 90
SOLiD: < 10
454 : < 10

And he mentioned that the solid and 454 machines are just basically
collecting dust.

I don't really have enough experience with either platform to draw and
judgements myself, but the guy giving the talk seemed pretty convinced
and thought it was relevant to share.


Steve Lianoglou
Graduate Student: Computational Systems Biology
 | Memorial Sloan-Kettering Cancer Center
 | Weill Medical College of Cornell University
Contact Info: http://cbio.mskcc.org/~lianos/contact

More information about the Bioc-sig-sequencing mailing list