[Bioc-devel] Call for collaborators/advice

Kasper Daniel Hansen k@@perd@n|e|h@n@en @end|ng |rom gm@||@com
Fri Mar 22 19:44:43 CET 2019


Why is this not "just" a function which transforms one GI into another GI?
Thats what it seems to me.

On Fri, Mar 22, 2019 at 12:31 PM Luke Klein <lklei001 using ucr.edu> wrote:

> I am writing a package that will extend the GenomicInteractions class.  I
> am a statistician, so I may not know best practices when it comes to
> extending existing classes (eg. should I make a new slot or simply add a
> column to the `elementMetadata`?  Are there existing functions that already
> do what I am attempting?).
>
> I am not familiar with Bioc-Devel decorum, so if asking this here is
> inappropriate, kindly let me know.
>
> About my project:
>
> In the first step, I am hoping to implement a HiC binning function on HiC
> data contained in a GenomicInteractions set.  I aim to:
>
>         - Reorder the anchor pairs (I will explain in more detail to
> anyone that wants to help)
>         - Collapse the regions to the desires bin width
>         - Sum the counts within each bin
>         - Update the anchors to agree with the new/updated regions
>
> This will set the stage for the new class that I hope to create for HiC
> domain calling, but I need to achieve the above tasks first.
>
> All the best to everyone!
>
> — Luke Klein
>     PhD Student
>     Department of Statistics
>     University of California, Riverside
>     lklei001 using ucr.edu
>
>
>
>
>
>
>
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>
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