MendelianRandomization: Mendelian Randomization Package

Encodes several methods for performing Mendelian randomization analyses with summarized data. Summarized data on genetic associations with the exposure and with the outcome can be obtained from large consortia. These data can be used for obtaining causal estimates using instrumental variable methods.

Version: 0.10.0
Depends: R (≥ 3.0.1), methods
Imports: knitr, rmarkdown, plotly (≥ 3.6.0), ggplot2 (≥ 1.0.1), robustbase (≥ 0.92-6), Matrix (≥ 1.2), iterpc (≥ 0.3), quantreg (≥ 5.01), rjson, glmnet, numDeriv, Rcpp
LinkingTo: Rcpp, RcppArmadillo
Published: 2024-04-12
DOI: 10.32614/CRAN.package.MendelianRandomization
Author: Stephen Burgess ORCID iD [aut, cre], Olena Yavorska [aut], James Staley ORCID iD [ctb], Fernando Hartwig ORCID iD [ctb], Jim Broadbent ORCID iD [ctb], Christopher Foley ORCID iD [ctb], Andrew Grant [ctb], Amy Mason ORCID iD [ctb], Ting Ye ORCID iD [ctb], Haoran Xue ORCID iD [ctb], Zhaotong Lin ORCID iD [ctb], Siqi Xu [ctb], Ashish Patel ORCID iD [ctb], Hyunseung Kang [ctb], Sheng Wang [ctb], Ville Karhunen ORCID iD [ctb]
Maintainer: Stephen Burgess <sb452 at>
License: GPL-2 | GPL-3
NeedsCompilation: yes
Materials: NEWS
In views: CausalInference, MetaAnalysis
CRAN checks: MendelianRandomization results


Reference manual: MendelianRandomization.pdf
Vignettes: Mendelian randomization vignette


Package source: MendelianRandomization_0.10.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): MendelianRandomization_0.10.0.tgz, r-oldrel (arm64): MendelianRandomization_0.10.0.tgz, r-release (x86_64): MendelianRandomization_0.10.0.tgz, r-oldrel (x86_64): MendelianRandomization_0.10.0.tgz
Old sources: MendelianRandomization archive

Reverse dependencies:

Reverse suggests: mrbayes


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