[R-sig-ME] mean and variance of random effects in glmer
Thierry.ONKELINX at inbo.be
Tue Jul 24 11:22:20 CEST 2012
Very large variance for the random effect in a binomial glmer is an indication for (quasi-)complete separation. Here is some info on that issue: http://www.ats.ucla.edu/stat/mult_pkg/faq/general/complete_separation_logit_models.htm
If the values of Problem and Across are constant within each level of PID, I would aggregate the data (sum per PID) and then use a simple glm()
ir. Thierry Onkelinx
Instituut voor natuur- en bosonderzoek / Research Institute for Nature and Forest
team Biometrie & Kwaliteitszorg / team Biometrics & Quality Assurance
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Thierry.Onkelinx op inbo.be
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Van: r-sig-mixed-models-bounces op r-project.org [mailto:r-sig-mixed-models-bounces op r-project.org] Namens Ken Kelley
Verzonden: dinsdag 24 juli 2012 8:29
Aan: r-sig-mixed-models op r-project.org
Onderwerp: [R-sig-ME] mean and variance of random effects in glmer
I'm fitting a straightforward glmer model with the family=binomial. I expected the mean of the random effect for the intercept to be near zero, but that isn't the case, as the mean is .91:
> (model.3 <- glmer(TA ~ 1 + Problem + Across + (1|PID), data=Data.Timed, family = binomial, nAGQ=100))
Generalized linear mixed model fit by the adaptive Gaussian Hermite approximation
Formula: TA ~ 1 + Problem + Across + (1 | PID)
AIC BIC logLik deviance
158.8 172.9 -75.38 150.8
Groups Name Variance Std.Dev.
PID (Intercept) 18.869 4.3439
Number of obs: 256, groups: PID, 64
Estimate Std. Error z value Pr(>|z|)
(Intercept) -1.1328 0.7304 -1.551 0.1209
Problem -0.5864 0.2449 -2.394 0.0167 *
Across -1.3768 0.4280 -3.217 0.0013 **
Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
Correlation of Fixed Effects:
Across -0.208 -0.150
That is, I'm doing a mixed effects logistic regression. The PID is the participant ID; there are 4 Problems (essentially timepoints: 0, 1, 2, 3) and Across is a time-varying covariate (0, 1, 2, or 3).
The mean of the random effects is:
Additionally, the variance of the random effect is in the model output as 18.869, yet when I calculate the variance of the random effects directly, I get a much smaller value:
Should I be surprised by either of the issues I note above? My concern is that I was planning on plotting the model implied curves using the fixed effects (so that the curves would represent an individual specific trajectory for a participant with a random effect of 0). Yet, there are no individuals with a random effect of zero and the mean is not zero. Thus, such a plot doesn't seem as useful as I initially thought it would.
Thanks for any thoughts on this,
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