[R-sig-ME] random effects estimation in Lmer

Hester Lingsma h.lingsma at erasmusmc.nl
Wed Dec 16 08:51:40 CET 2009

Dear all,
Thanks for the suggestions. I will take a look at the coxme package.
Hester Lingsma

on 16-12-2009 08:01 David Duffy said the following:
> On Tue, 15 Dec 2009, Henric (Nilsson) Winell wrote:
>> On 2009-12-15 09:23, David Duffy wrote:
>>> Have you looked at the kinship package at all?  It uses lme, but 
>>> analyses age at onset data from families more nicely than lmer can 
>>> (see the coxme() function and the vignette/documentation).
>> Actually, the latest version of the coxme() function now lives in 
>> Terry Therneau's new 'coxme' package.
>> It no longer depends on 'nlme', but uses its own fitting routines and 
>> sparse matrix representation, and has a lme4-like syntax for the 
>> specification of random effects.
> Good to know!
> The OP may want to use the kinship package to generate kinship 
> matrices, and to look at the breast cancer example therein.
> Cheers, David Duffy.

Hester F. Lingsma, MSc
Dept of Public Health
Room AE-141
Erasmus MC
P.O. Box 2040
3000 CA Rotterdam
The Netherlands
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