[R-sig-ME] random effects estimation in Lmer

David Duffy David.Duffy at qimr.edu.au
Wed Dec 16 08:01:01 CET 2009

On Tue, 15 Dec 2009, Henric (Nilsson) Winell wrote:

> On 2009-12-15 09:23, David Duffy wrote:
>> Have you looked at the kinship package at all?  It uses lme, but analyses 
>> age at onset data from families more nicely than lmer can (see the coxme() 
>> function and the vignette/documentation).
> Actually, the latest version of the coxme() function now lives in Terry 
> Therneau's new 'coxme' package.
> It no longer depends on 'nlme', but uses its own fitting routines and sparse 
> matrix representation, and has a lme4-like syntax for the specification of 
> random effects.

Good to know!

The OP may want to use the kinship package to generate kinship matrices, 
and to look at the breast cancer example therein.

Cheers, David Duffy.

| David Duffy (MBBS PhD)                                         ,-_|\
| email: davidD at qimr.edu.au  ph: INT+61+7+3362-0217 fax: -0101  /     *
| Epidemiology Unit, Queensland Institute of Medical Research   \_,-._/
| 300 Herston Rd, Brisbane, Queensland 4029, Australia  GPG 4D0B994A v

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