[R-meta] Fwd:

[Awais Wahab]

Hello!
I need some help please.
I have 5-6 one sided P-values from different studies and need to do their
meta-analysis.

I am using these (Example) codes in R as below, but they are not working,

*> library(metap)*

*pvals <- c(0.1, 0.1, 0.9, 0.9, 0.9, 0.9)  *

*> istwo <- c(TRUE, FALSE, TRUE, FALSE, TRUE, FALSE)*

*> toinvert <- c(FALSE, TRUE, FALSE, FALSE, TRUE, TRUE)*

*> two2one(pvals, two = istwo, invert = toinvert)*

*> print(validity)*

*> plotp(validity)*

*> schweder(validity)*


*OR this below,*



*Fisher's method, T = -2*log(p-value1)-2*log(p-value2)-...-2*log(p-valuem)
where m is the number of p-values. Under the null hypothesis, this will be
distributed as chi-squared with m degrees of freedom, so you would then do
T.pval = 1-pchisq(T,m)*


Are these codes correct ?  I am not sure where exactly to put my p-values.
It will be great if someone can help me with the correct codes.


I will be much grateful for your kind support.

best regards.

On Tue, Sep 28, 2021 at 11:27 AM Dr. Gerta Rücker <
ruecker using imbi.uni-freiburg.de> wrote:

> Hi Imran,
>
> There was already an answer by Michael Dewey with a useful link to
> MetaAnalysis Task View https://cran.r-project.org/view=MetaAnalysis
>
> Best,
>
> Gerta
>
> Am 28.09.2021 um 10:06 schrieb Awais Wahab:
> > Hello!
> >
> > Is it possible to perform meta-analysis with available P-values in each
> > study as effect size, instead of HR, OR etc. ?
> >
> > Thanks in advance.
> > Best regards,
> > Imran
> >
> >       [[alternative HTML version deleted]]
> >
> > _______________________________________________
> > R-sig-meta-analysis mailing list
> > R-sig-meta-analysis using r-project.org
> > https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
>
> --
>
> Dr. rer. nat. Gerta Rücker, Dipl.-Math.
>
> Guest Scientist
> Institute of Medical Biometry and Statistics,
> Faculty of Medicine and Medical Center - University of Freiburg
>
> Zinkmattenstr. 6a, D-79108 Freiburg, Germany
>
> Mail:     ruecker using imbi.uni-freiburg.de
> Homepage:
> https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker
>
>

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