[R-meta] overall efect size from subgroup analysis

[Gerta Ruecker]

Hi

Am 27.04.2021 um 16:08 schrieb Michael Dewey:
> Dear Diego
>
> [...]
> Your data is close to unreadable as you posted in HTML and that 
> becomes mangled. If you need to re-post you have to find a way to send 
> plain text. I do not use Gmail but I am sure it is possible.

Yes, it was difficult to read. But, only a question: What then does it 
mean that it is written at the bottom of Diego's mail "[[alternative 
HTML version deleted]]"? See below.

Gerta

>
> On 27/04/2021 08:56, Diego Grados Bedoya wrote:
>> Dear all,
>>
>> Several meta-analyses in my field do not report the overall effect 
>> size of
>> the intervention. For instance, they report  the subgroup analysis 
>> (values
>> as a percentage change for log response ratio):
>>
>> subgroup
>>
>> CI_lower_limit
>>
>> effect_size
>>
>> CI_upper_limit
>>
>> number_comparisons
>>
>> group_1
>>
>> -73
>>
>> -48
>>
>> -12
>>
>> 5
>>
>> group_2
>>
>> -38
>>
>> -30
>>
>> -21
>>
>> 43
>>
>> group_3
>>
>> -24
>>
>> -15
>>
>> -6
>>
>> 73
>>
>> Assuming a random effect model (and considering that the CI of the
>> subgroups could have been estimated by bootstrapping), I wonder if it is
>> possible to estimate the overall effect size and the CIs just with this
>> information?
>>
>> Thank you in advance,
>>
>> Kind regards,
>>
>> Diego
>>
>>     [[alternative HTML version deleted]]
>>
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>>
>
-- 

Dr. rer. nat. Gerta Rücker, Dipl.-Math.

Institute of Medical Biometry and Statistics,
Faculty of Medicine and Medical Center - University of Freiburg

Stefan-Meier-Str. 26, D-79104 Freiburg, Germany

Phone:    +49/761/203-6673
Fax:      +49/761/203-6680
Mail:     ruecker using imbi.uni-freiburg.de
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