[R-meta] Publication bias/sensitivity analysis in multivariate meta-analysis

Michael Dewey ||@t@ @end|ng |rom dewey@myzen@co@uk
Sun Jun 14 12:54:30 CEST 2020

Dear Huang

Comments in-line

On 13/06/2020 20:57, Huang Wu wrote:
> Hi all,
> Greetings. I have some questions about publication bias/sensitivity analysis. First, are publication bias and sensivity analysis the same thing? If not, how are they different?

Publication bias is a subset of small study effects where you know the 
aetiology of the small study effects. If you do not then it is safer to 
refer to small study effects. A sensitivity analysis could be almost 
anything but usually it manes fitting the model to one or more data-sets 
similar to the original one. Examples are leave-one-out analysis, or 
using only a subset of supposed higher quality studies.

> Second, I saw people use funnel plot, fail-safe N, Egger�s regression test to test publication bias (http://www.metafor-project.org/doku.php/features), are these methods applicable to multivariate meta-analysis? 

Yes they are.

> Third, what do you recommend to do publication bias/sensivity analysis in multivariate meta-analysis? Thanks

I think what analysis you do will depend on the scientific question.


> Best wishes
> Huang
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