[R-meta] Need suggestion on forest plot results
Guido Schwarzer
@c @end|ng |rom |mb|@un|-|re|burg@de
Wed Jun 3 13:59:38 CEST 2020
(I haven't noticed that I got a personal email by Awais - find below my
reply)
Awais,
As expected this is a rounding problem and you can do nothing about it
but get more precise estimates (which are probably not available).
The distances between lower and upper CI limit to the log hazard ratio
are different (due to rounding to two digits):
lnHR = log(1.93)
lowHR = log(1.23)
uppHR = log(3.00)
lnHR - lowHR
uppHR - lnHR
The standard error is approximated from half the distance between lower
and upper 95% CI:
(uppHR - lowHR) / (2 * qnorm(0.975))
meta::metagen(lnHR, lower = lowHR, upper = uppHR)$seTE
Which results in the minor shift of the confidence limits:
meta::metagen(lnHR, lower = lowHR, upper = uppHR, sm = "HR")
Best wishes, Guido
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