[R-meta] meta-regression for incidence rate

[Giorgio Maria Agazzi]

Thank you very much!

Gma

Il lun 1 giu 2020, 17:05 Michael Dewey <lists using dewey.myzen.co.uk> ha scritto:

> Dear Giorgio
>
> This may be related to a long discussion on this list recently. You can
> see the original post
> https://stat.ethz.ch/pipermail/r-sig-meta-analysis/2020-May/002082.html
> and then follow the rest of a quite extensive thread. I am not
> sufficiently expert in time-to-event studies to say whether it does
> answer your question but it might be informative.
>
> Michael
>
> On 31/05/2020 19:27, Giorgio Maria Agazzi wrote:
> > Dear all,
> > I am planning to do a meta-regression with the intent to compare trial
> > patient characteristics to the incidence of an outcome in the time period
> > between t=0 and t=2 years. Every study reports the number at risk at t=0
> > and t=2 years and the kaplan-meier curve, so I'm able to digitize the
> curve
> > and extract the percentages of events.
> > I was thinking of doing a meta-regression and using as effect size the
> > freeman-tukey transformed incidence rate. I'm not sure this is the best
> way
> > and I have also another question, how can I calculate the total number at
> > risk as requested by metafor? for the number of events I can calculate it
> > by digitizing the plot and calculating the percentage of people that had
> > the outcome.
> >
> > Thank you very much!
> >
> > gma
> >
> >       [[alternative HTML version deleted]]
> >
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>
> --
> Michael
> http://www.dewey.myzen.co.uk/home.html
>

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