[R-meta] convergence in Mada

[Gerta Ruecker]

Thank you! You had misspelled the first author's name, that's why I 
couldn't find it.

Gerta

Am 19.06.2019 um 15:22 schrieb Philipp Doebler:
> Hi Gerta,
>
> the paper appeared in Methods Inf Med:
>
> Vogelgesang F, Schlattmann P, Dewey M (2018).  The Evaluation of 
> Bivariate Mixed Models in Meta-analyses of Diagnostic Accuracy Studies 
> with SAS, Stata and R. Methods Inf Med. 2018 May;57(3):111-119. doi: 
> 10.3414/ME17-01-0021.
>
> Kind wishes,
>    Philipp
>
>
>
>
> On Wed, Jun 19, 2019 at 3:19 PM Gerta Ruecker 
> <ruecker using imbi.uni-freiburg.de <mailto:ruecker using imbi.uni-freiburg.de>> 
> wrote:
>
>     Dear Philipp,
>
>     Could you please give a link or full bibliographic details for the
>     paper
>     you cited (Vogelsang et al., 2018)? I couldn't find it.
>
>     Best,
>
>     Gerta
>
>
>     Am 19.06.2019 um 14:59 schrieb Philipp Doebler:
>     > Hi James,
>     >
>     > I have rarely had convergence problems. There are three
>     potential problems:
>     >
>     > (1) Low number of studies (5 model parameters...) but mada
>     throws a warning
>     > if I remember correctly.
>     > (2) Little variance in the false positive rates and/or
>     sensitivities.
>     > Especially relevant if all studies have the same sensitivity of,
>     say, 95%.
>     > This can sometimes lead to a degenerate covariance matrix of the
>     bivarate
>     > random effect.
>     > (3) A perfect between study correlation of logit(sens) and
>     logit(fpr). If
>     > there is any suspicion, calculate the correlation matrix with
>     cov2cor.
>     >
>     > Also have a look at all standard errors and confidence
>     intervals. The
>     > recent simulation study of Vogelsang et al. (2018) discusses
>     convergence
>     > issues of mada (and other packages).
>     >
>     > Kind wishes,
>     >     Philipp
>     >
>     >
>     >
>     >
>     > On Wed, Jun 19, 2019 at 2:32 PM James Meyer <
>     > outlook_655291802F3BAFF3 using outlook.com
>     <mailto:outlook_655291802F3BAFF3 using outlook.com>> wrote:
>     >
>     >> How can you tell if convergence has been accomplished using the
>     reitsma()
>     >> function in mada ? Which package do you recommend using for DTA
>     >> meta-analysis if you have a small number of studies?
>     >>
>     >> Sincerely
>     >> James C Meyer
>     >> Sent from Mail<https://go.microsoft.com/fwlink/?LinkId=550986> for
>     >> Windows 10
>     >>
>     >>
>     >>          [[alternative HTML version deleted]]
>     >>
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>     >
>     -- 
>
>     Dr. rer. nat. Gerta Rücker, Dipl.-Math.
>
>     Institute of Medical Biometry and Statistics,
>     Faculty of Medicine and Medical Center - University of Freiburg
>
>     Stefan-Meier-Str. 26, D-79104 Freiburg, Germany
>
>     Phone:    +49/761/203-6673
>     Fax:      +49/761/203-6680
>     Mail: ruecker using imbi.uni-freiburg.de
>     <mailto:ruecker using imbi.uni-freiburg.de>
>     Homepage: https://www.imbi.uni-freiburg.de/persons/ruecker/person_view
>
>
>
> -- 
> Prof. Dr. Philipp Doebler
> Technische Universität Dortmund
> Fakultät Statistik
> Vogelpothsweg 87
> 44227 Dortmund
>
> Tel.: +49 231-755 8259
> Fax: +49 231-755 3918
> doebler using statistik.tu-dortmund.de <mailto:doebler using statistik.tu-dortmund.de>
> www.statistik.tu-dortmund.de/1261.html 
> <http://www.statistik.tu-dortmund.de/1261.html>
>
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-- 

Dr. rer. nat. Gerta Rücker, Dipl.-Math.

Institute of Medical Biometry and Statistics,
Faculty of Medicine and Medical Center - University of Freiburg

Stefan-Meier-Str. 26, D-79104 Freiburg, Germany

Phone:    +49/761/203-6673
Fax:      +49/761/203-6680
Mail:     ruecker using imbi.uni-freiburg.de
Homepage: https://www.imbi.uni-freiburg.de/persons/ruecker/person_view


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