[R-meta] convergence in Mada

[Philipp Doebler]

Hi Gerta,

the paper appeared in Methods Inf Med:

Vogelgesang F, Schlattmann P, Dewey M (2018).  The Evaluation of Bivariate
Mixed Models in Meta-analyses of Diagnostic Accuracy Studies with SAS,
Stata and R. Methods Inf Med. 2018 May;57(3):111-119. doi:
10.3414/ME17-01-0021.

Kind wishes,
   Philipp




On Wed, Jun 19, 2019 at 3:19 PM Gerta Ruecker <ruecker using imbi.uni-freiburg.de>
wrote:

> Dear Philipp,
>
> Could you please give a link or full bibliographic details for the paper
> you cited (Vogelsang et al., 2018)? I couldn't find it.
>
> Best,
>
> Gerta
>
>
> Am 19.06.2019 um 14:59 schrieb Philipp Doebler:
> > Hi James,
> >
> > I have rarely had convergence problems. There are three potential
> problems:
> >
> > (1) Low number of studies (5 model parameters...) but mada throws a
> warning
> > if I remember correctly.
> > (2) Little variance in the false positive rates and/or sensitivities.
> > Especially relevant if all studies have the same sensitivity of, say,
> 95%.
> > This can sometimes lead to a degenerate covariance matrix of the bivarate
> > random effect.
> > (3) A perfect between study correlation of logit(sens) and logit(fpr). If
> > there is any suspicion, calculate the correlation matrix with cov2cor.
> >
> > Also have a look at all standard errors and confidence intervals. The
> > recent simulation study of Vogelsang et al. (2018) discusses convergence
> > issues of mada (and other packages).
> >
> > Kind wishes,
> >     Philipp
> >
> >
> >
> >
> > On Wed, Jun 19, 2019 at 2:32 PM James Meyer <
> > outlook_655291802F3BAFF3 using outlook.com> wrote:
> >
> >> How can you tell if convergence has been accomplished using the
> reitsma()
> >> function in mada ? Which package do you recommend using for DTA
> >> meta-analysis if you have a small number of studies?
> >>
> >> Sincerely
> >> James C Meyer
> >> Sent from Mail<https://go.microsoft.com/fwlink/?LinkId=550986> for
> >> Windows 10
> >>
> >>
> >>          [[alternative HTML version deleted]]
> >>
> >> _______________________________________________
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> >> R-sig-meta-analysis using r-project.org
> >> https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
> >>
> >
> --
>
> Dr. rer. nat. Gerta Rücker, Dipl.-Math.
>
> Institute of Medical Biometry and Statistics,
> Faculty of Medicine and Medical Center - University of Freiburg
>
> Stefan-Meier-Str. 26, D-79104 Freiburg, Germany
>
> Phone:    +49/761/203-6673
> Fax:      +49/761/203-6680
> Mail:     ruecker using imbi.uni-freiburg.de
> Homepage: https://www.imbi.uni-freiburg.de/persons/ruecker/person_view
>
>

-- 
Prof. Dr. Philipp Doebler
Technische Universität Dortmund
Fakultät Statistik
Vogelpothsweg 87
44227 Dortmund

Tel.: +49 231-755 8259
Fax: +49 231-755 3918
doebler using statistik.tu-dortmund.de
www.statistik.tu-dortmund.de/1261.html


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