[R-sig-genetics] Introduction to Multi’omics Data Analysis from Microbial Communities (MOMC01)
Oliver Hooker
o||verhooker @end|ng |rom pr@t@t|@t|c@@com
Tue Jan 24 17:35:24 CET 2023
ONLINE COURSE – Introduction to Multi’omics Data Analysis from Microbial
Communities (MOMC01) This course will be delivered live
https://www.prstatistics.com/course/introduction-to-multiomics-data-analysis-from-microbial-communities-momc01/
Delivered by Dr. Melanie Schirmer
Please feel free to share!
Friday 10th March 2023
The aim of this one-day workshop is to provide a thorough introduction to
computational approaches for the analysis of microbial community profiles
with a focus on metagenomic sequencing data. We will explain how taxonomic
and functional profiles are generated from raw sequencing data, introduce
different bioinformatic approaches to process sequencing data, followed by
multivariate statistical analysis and different visualization techniques.
The course will consist of a mixture of lectures and hands-on tutorials.
The practical part of the
course will focus on the analysis of publicly available multi-omics
profiles.
By the end of the course participants should:
1. Be familiar with different workflows involved in the analysis of
large-scale multi-omics studies.
2. Understand how to generate taxonomic, functional and strain profiles from
metagenomic sequencing data.
3. Be familiar with applying a multivariate statistical framework to
generate hypothesesand account for confounding covariates.
4. Be able to use exploratory data visualizations techniques and visualize
results from the statistical analysis using R.
Lecture 1 – general Introduction
Lecture 2 – Introduction to microbial community analysis
Practical 1 – Introduction to R and R notebook
Lecture 3 – Metagenomic data visualisation and exploratory analysis with cMD
Practical 2 – Metagenomic data visualisation
Lecture 4 – Statistics for microbial multi-comics data, methods for
multi-comics integration
Practical 3 – Multivariate analysis (Linear models and/or MaAsLin2
Lecture 5 – Large-scale multi-omics studies
Conclusions – Discussion, questions, wrap up!
--
Oliver Hooker PhD.
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