[R] help

[Sarah Bazzocco]

Hello, 

  

I am a R-beginner and I need some help. The question is very simple: I need to do a pearson correlations (r,p-value and FDR with BH) from an Expression array (with several thousand genes for lets say 20 cell lines) with some features of those cell lines. 



My problem I have is the organization of the excel sheets and how to introduce the data into R and run the script. I though the easiest and more organized for me would be two expcel sheets: 

1- Only Expression data (in rows the genes and in colums cell lines) 

2- Only the features (In row the features (e.g. a) growth rate, b) sensitivity to some drugs) and in columns the cell lines). 



-->That would creat both sheets with 20 colums. 



Now I would like to get a correlation of the gene 1: the expression of all lines with the growth rate. 

the same for gene2... and soforth. I sould obtain as many r,p and BH(FDR) as genes there are. 

the same I would need to do for the sensitivity... and so on. 



Do you think this is doable? I am not at all a bioinformatic expert, so all help is very welcome. 



Thank you very much! 



Kind regards, 



Sarah 



-- 


Sarah Bazzocco, PhD student 
Group of Molecular Oncology, 
CIBBIM-Nanomedicine, 
Vall d'Hebron Hospital Research Institute, 
Passeig Vall d'Hebron 119-129, 
Barcelona 08035, Spain. 
Tel: +34-93-489-4056 

Fax: +34-93-489-3893 
Email: sarah.bazzocco at vhir.org 


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