[R] Need to replicate Boltzman Signmodial Curve fit from Graph Pad

John Kane jrkrideau at inbox.com
Tue Apr 23 18:54:50 CEST 2013


No idea of the area but does this link help? http://bioinformatics.oxfordjournals.org/content/24/13/1549.full

John Kane
Kingston ON Canada


> -----Original Message-----
> From: rnoobier at gmail.com
> Sent: Tue, 23 Apr 2013 10:55:59 -0400
> To: r-help at r-project.org
> Subject: [R] Need to replicate Boltzman Signmodial Curve fit from Graph
> Pad
> 
> Hello useRs (please don't kill me),
> 
> I've fairly new to R having only a few months of playing around with R.
> What little I've learned has been extremely useful.
> 
> If someone could point me as to how to replicate the Boltzman Sigmodial
> curve fit as provided by Graphpad software I'd be eternally grateful.
> 
> Where  we currently use Graphpad for only this one function,its seems
> highly inefficient for a $100 piece of software to be used for only one
> function (which isn't nearly as bad as the company's pandemic reliance on
> Excel for nearly everything else).
> 
> so anyway, what I'd normally do is take a set of data like this:
> 
>  pH counts  3.8 968  5.0 1347  5.8 2867  6.6 9203  7.0 15817  7.4 20297
> 8.2
> 31916  9.2 35756
> then fit this to a Boltzman sigmodial in Graphpad. Graphpad spits out a
> much longer set of vectors and also information about v50 and confidence
> intervals etc (if anyone is familiar with that software). This is what
> i'd
> like to replicate.
> 
> It might be that I just don't know what i'm doing,so feel free to call me
> an idiot but any help is greatly appreciated!
> 
> -JJ
> 
> 	[[alternative HTML version deleted]]
> 
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