[BioC] GWASTools: Sandwich SE

[Adrienne Stilp]

Hi Arash,

The p-values from assocTestRegression are indeed two-sided. (The function uses pchisq to calculate them.)

Thanks,
Adrienne

On Jul 13, 2014, at 10:25 AM, Arash Nazeri <arashnazeri at gmail.com> wrote:

> Dear Adrienne, 
> 
> We have been using GWASTools for an interaction model with sandwich standard errors (model robust). We wanted to make sure that the p values generated from the Wald tests are two-sided or not.
> 
> My guess is that this is an inherent issue with Wald tests, as there is no directionality left.
> 
> Any help is greatly appreciated.
> 
> Cheers,
> Arash