[BioC] Running DESeq with 1000 samples

[Maoqi Xu [guest]]

Hi,
I'm using DESeq to find the differential expressed genes between 2 populations. The RNA-seq data set has a total sample size of around 1000. However, even I set the memory limit of R to 6 Gb, it still reports the error that it cannot allocate vector of certain size. I wonder if it's possible to use DESeq on this huge data set and how much memory should be enough.

Thank you!

 -- output of sessionInfo(): 

NA

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