[BioC] getting genotypes with oligo package
Lilia Romdhane [guest]
guest at bioconductor.org
Wed Jul 3 11:32:25 CEST 2013
Hi, I have genotyped samples from Affy6.0 platform using crlmm algorithm
from Oligo and I am facing difficulties in interpretation. I am trying
to match the SNP calls from crlmm with their respective alleles. I would appreciate any comments and help.
Given a SNP has A and B allele, is it that A is always a major allele
and B is always a minor allele or is it that the allele A and B are
alphabetically assigned; the first alphabet (A,T,G,C) gets assigned as
A allele and the next alphabet is assigned as B allele?
I used the code provided in the oligo package help. I would greatly obtain a result in a tabulated file like below:
NA06985.CEL NA06991.CEL
SNP_A-1507972 TT TC
SNP_A-1510136 AG GG
Thanks
-- output of sessionInfo():
> sessionInfo()
R version 3.0.1 (2013-05-16)
Platform: x86_64-w64-mingw32/x64 (64-bit)
locale:
[1] LC_COLLATE=French_France.1252 LC_CTYPE=French_France.1252
[3] LC_MONETARY=French_France.1252 LC_NUMERIC=C
[5] LC_TIME=French_France.1252
attached base packages:
[1] parallel stats graphics grDevices utils datasets methods
[8] base
other attached packages:
[1] pd.genomewidesnp.6_1.10.0 RSQLite_0.11.4
[3] DBI_0.2-7 oligo_1.24.0
[5] Biobase_2.20.1 oligoClasses_1.22.0
[7] BiocGenerics_0.6.0
loaded via a namespace (and not attached):
[1] affxparser_1.32.3 affyio_1.28.0 BiocInstaller_1.10.2
[4] Biostrings_2.28.0 bit_1.1-10 codetools_0.2-8
[7] ff_2.2-11 foreach_1.4.1 GenomicRanges_1.12.4
[10] IRanges_1.18.1 iterators_1.0.6 preprocessCore_1.22.0
[13] splines_3.0.1 stats4_3.0.1 zlibbioc_1.6.0
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