[BioC] statistical test for time course data
Gordon K Smyth
smyth at wehi.EDU.AU
Tue Feb 5 04:02:45 CET 2013
Dear Rich,
I have added a time course example using splines to the limma User's
Guide, see page 48:
http://bioconductor.org/packages/2.12/bioc/vignettes/limma/inst/doc/usersguide.pdf
Best wishes
Gordon
------------------ original message ------------------
[BioC] statistical test for time course data
Richard Friedman friedman at cancercenter.columbia.edu
Sun Feb 3 20:18:03 CET 2013
Dear Gordon,
Thank you very much for the clarification. Now that I think of it,
the one-against all is straightforward. However, If there are any worked
examples you could point me towards for polynomial and spline modeling of
the time series I would greatly appreciate it. I am especially interested
in testing the hypothesis that the temporal behavior of 2 treatments are
different.
Best wishes,
Rich
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