[BioC] Custom CDF for alternative splicing with xps
Binbin [guest]
guest at bioconductor.org
Thu Dec 6 17:58:54 CET 2012
Hello there, using xps and affymetrix official PGF files, I have built a scheme for hs exon_st1.0_v2 analysis at the transript level. Now we want to study isoforms by looking at the data at the exon level. One issue we want to avoid is the multiple-mapping of same probes and a reasonable up-to-date annotation. Brainarray's custom CDF (v16 Ensembl exon) seems a good choice. My question is - can import.expr.scheme() in xps build a root using these custom CDF files? Have gone through the xps reference/manual but still not sure.
Many thanks for suggestions.
-- output of sessionInfo():
R version 2.15.0 (2012-03-30)
Platform: x86_64-unknown-linux-gnu (64-bit)
locale:
[1] LC_CTYPE=en_US.utf8 LC_NUMERIC=C
[3] LC_TIME=en_US.utf8 LC_COLLATE=en_US.utf8
[5] LC_MONETARY=en_US.utf8 LC_MESSAGES=en_US.utf8
[7] LC_PAPER=C LC_NAME=C
[9] LC_ADDRESS=C LC_TELEPHONE=C
[11] LC_MEASUREMENT=en_US.utf8 LC_IDENTIFICATION=C
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] xps_1.18.0
loaded via a namespace (and not attached):
[1] tools_2.15.0
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