[BioC] gene set enrichment analysis of RNA-Seq data

[Julie Leonard]

Thanks Gordon-
    I'll definitely look into using camera.  I have a naive question though.  If
I use voom() to transform the RNA-Seq count data, does this transformation
change the data from discrete to continuous?  And if so, can I just use the E
values in the EList object that is outputted from voom() as input to GSEA (Broad
version)?  I would assume I wouldn't need the weights b/c GSEA does not assume a
specific distribution (it is empirically calculated via subject sampling), so I
wouldn't need to adjust the data for heteroscedasticity to fit a "normal" or any
other pre-set distribution??  

Thanks,
Julie