[BioC] Detecting Up-Regulated Genes

Freudenberg, Johannes (NIH/NIEHS) [E] johannes.freudenberg at nih.gov
Thu Sep 8 18:14:20 CEST 2011

Hi Anirban, 

A good start would be the limma package.  

> library(limma)
> limmaUsersGuide()

Then go to chapter 8.8 "Time Course Experiments"


-----Original Message-----
From: ANIRBAN BHAR [mailto:aec.ani at gmail.com] 
Sent: Thursday, September 08, 2011 12:07 PM
To: bioconductor at r-project.org
Subject: [BioC] Detecting Up-Regulated Genes

Hi all,

I have an Time-course dataset where each gene has expression values over some time-points and each time-point has some replicates. Now how can we detect up-regulated genes between two time points using some standard procedure (may be some statistical test)? I am interested to have an idea about the work-flow..

Thanks in advance..

Best Regards,


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