[BioC] Ask for your help

[Sean Davis]

Hi, Shujiema.

This is an email list for discussing Bioconductor, so you might need
to try a different place to get your answers.

Sean


On Mon, Sep 5, 2011 at 1:26 AM, 马淑杰 <msmashujie at gmail.com> wrote:
> Dear Dr. Mattia Pelizzola：
>
>
>
> I am sorry to trouble you!
>
>
>
> I am great interested in the methods in your paper named Genome-wide screen
> of promoter methylation identifies novel markers in melanoma.
>
> I have downloaded this paper from the linking as fellow:
>
> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720187/
>
>
>
> The methods of identification of biomarkers is very good. But I have
> something wrong about it.
>
>
>
> *Identification of biomarkers*
>
> Intermediate and proximal promoter regions of each RefSeq were divided into
> six regions based on the distance from the TSS (-500 to -350, -200 to -50, -50
> to +100, +100 to +250, and +250 to +500 bp, with respect to the TSS). The
> AMS for a given region was determined as the average of the AMS for the
> probes in that genomic area.
>
>
>
> I don't know you according to what rules to divide the RefSeq.Can you give
> me an example to descipe it?
>
>
>
> I will appreciate any help from you, thank you very much !
>
> Best wishes
>
> Yours sincerely
>
>                  shujiema
>
>        [[alternative HTML version deleted]]
>
>
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