[BioC] heatmap.2 Z-score vs logFC

Neel Aluru naluru at whoi.edu
Tue Oct 18 17:33:26 CEST 2011

Hello Bioc Users,

I am having a hard time understanding why heatmap.2 uses row (or column) 
Z-score instead of directly plotting logFC values?  Based on the formula 
for calculating Z-score, I understand that it is used for scaling or 
smoothing. But, isn't it the same when using logFC. Please correct if I 
am wrong. I really appreciate if anyone can give me a clear explanation.

Sorry for asking a silly question. I

Neel Aluru
Visiting Investigator
Biology Department
Woods Hole Oceanographic Institution
45 Woods Hole Road
Woods Hole 02543

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