[BioC] present / absent calls and detection p-values

Wei Shi shi at wehi.EDU.AU
Wed Oct 5 00:03:14 CEST 2011


Dear Andreas,

If what you have is an Illumina BeadChip dataset and also you have negative control probes included in your ExpressionSet object, then it will be possible to derive detection p values  because Illumina calculates detection p values based on these negative controls.

Cheers,
Wei

On Oct 5, 2011, at 12:40 AM, Andreas Heider wrote:

> Dear mailing list,
> is there a straight forward way of deriving present / absent calls or
> detection p-values from an existing ExpressionSet? The ExpressionSet will
> have no "se.exprs" or "pval" slots available.
> Also is there a way to convert in between the two (present/absent and
> p-value)?
> 
> Thanks, Andreas
> 
> 	[[alternative HTML version deleted]]
> 
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