[BioC] which statistical test to perform?
anand mt [guest]
guest at bioconductor.org
Wed Nov 23 11:14:15 CET 2011
hi all,
i'm new to this microarray data analysis.
recently i've been given data consisting of 11 tissues.
now i've normalized the data, filtered data using mas5 AP calls. My question is, which statistical test i must perform
to calculate the significance values ??
sample data is as below:
accumbens amygdala cerebellum corpus.collosum hippocampus midbrain p.lobe putamen s.nigra t.lobe thalamus
1007_s_at 11.93852233 12.21404093 11.46118612 13.41594885 12.42216256 12.89589133 11.58715914 11.85803472 12.79920479 12.07087932 12.55338306
1053_at 7.490706858 7.526181155 7.551069308 7.891002293 7.49104271 7.971097552 8.088918072 7.660258014 7.92423132 7.54689645 7.128753703
117_at 8.486898268 8.773089087 7.642339349 8.560352732 7.676296801 7.865961146 7.250275943 7.929165261 7.874073766 7.940298941 8.10731601
I got some web results, from which i came to know that, chi-square test is of more relevant in this case (to compare 3 or more unmatched groups, binomial). Is it correct to choose chi-square test ??
Sorry if my question is too lame.
thanks in advance.
-- output of sessionInfo():
R version 2.13.1 (2011-07-08)
Platform: i386-pc-mingw32/i386 (32-bit)
locale:
[1] LC_COLLATE=English_United States.1252 LC_CTYPE=English_United States.1252 LC_MONETARY=English_United States.1252 LC_NUMERIC=C
[5] LC_TIME=English_United States.1252
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] MASS_7.3-13
loaded via a namespace (and not attached):
[1] tools_2.13.1
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