[BioC] Minor allele frequency comparison
Scott Harding
thesis1977 at gmail.com
Fri Dec 9 16:01:24 CET 2011
Hi all,
We are using two methods to identify SNPs. One is based on
resequencing the genome and aligning the reads to the sequenced genome
to identify SNPs (data available for 44 individuals). Another is based
on SNP array with selected loci (30000 loci, 870 individuals). I want
to compare the results from the resequencing based minor allele
frequency and Array based minor allele frequency. What statistical
test should I use?
My table looks like
Chromosome position Major/minor
Resequencing SNP array
chromosome 1 198432 C/T
75/13 1460/280
chromosome 1 14282752 A/G
69/19 1380/360
chromosome 1 595434 T/G
83/5 1680/60
I really appreciate any guidance.
Thanks
Scott
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